Nature

Do cutting-edge CAR-T-cell therapies cause cancer? What the data say

Regulators have identified around 30 cases of cancer linked to this blockbuster treatment. But is CAR T to blame? The hunt is on for answers.

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Dalmeet Singh Chawla
News29 Apr 2024
First fetus-to-fetus transplant demonstrated in rats

The tissue developed into functioning kidneys and produced urine.

Smriti Mallapaty
News30 Apr 2024
Optical clocks at sea

Sea-based optical clocks combining a molecular iodine spectrometer, fibre frequency comb and electronics for monitoring and control demonstrate high precision in a smaller volume than active hydrogen masers.

Jonathan D. Roslund
Arman Cingöz
Martin M. Boyd
ArticleOpen Access24 Apr 2024
Daily briefing: Gaze upon the most detailed Moon maps ever made

The new Geologic Atlas took more than 100 researchers over a decade to compile. Plus, how gliding marsupials got their ‘wings’ and H5N1 bird flu virus material has been detected in US milk.

Flora Graham
Nature Briefing26 Apr 2024
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News & Comment

Why doing science is difficult in India today

With an election under way, the future of Indian science is on the ballot. Encouraging research and critical thinking should be a priority for the new government.

Yamini Aiyar

World View30 Apr 2024
Do cutting-edge CAR-T-cell therapies cause cancer? What the data say
Cassandra Willyard
News Feature30 Apr 2024
First fetus-to-fetus transplant demonstrated in rats
Smriti Mallapaty
News30 Apr 2024
What China’s mission to collect rocks from the far side could reveal about the Moon
Ling Xin
News30 Apr 2024
Epic blazes threaten Arctic permafrost. Can fire-fighters save it?
Jeff Tollefson
News29 Apr 2024
Superconductivity hunt gets boost from China's $220 million physics 'playground'
Gemma Conroy
News29 Apr 2024
How reliable is this research? Tool flags papers discussed on PubPeer
Dalmeet Singh Chawla
News29 Apr 2024

Latest Reviews & Analysis

- Elephant-nose fish ‘see’ farther by electric sensing when in groups
  
  The elephant-nose fish senses its environment by emitting electrical pulses. A multi-pronged investigation suggests that this remarkable sensing ability is amplified in social groups by individuals ‘listening in’ on the pulses of their neighbours.
  
  Research Briefing29 Apr 2024
- Robust optical clocks promise stable timing in a portable package
  
  A highly precise timekeeping instrument has been adapted for the real world. The compact and robust device is smaller than its commercial counterparts and performs comparably in the laboratory and aboard a naval ship.
  Bonnie L. S. Marlow
  Jonathan Hirschauer
  
  News & Views24 Apr 2024
- Targeting RNA opens therapeutic avenues for Timothy syndrome
  
  A therapeutic strategy that alters gene expression in a rare and severe neurodevelopmental condition has been tested in stem-cell-based models of the disease, and has been shown to correct genetic and cellular defects.
  Silvia Velasco
  
  News & Views24 Apr 2024
- Bioengineered ‘mini-colons’ shed light on cancer progression
  
  Cells grown on a 3D scaffold have generated a ‘mini-colon’ that mimics key features of the organ. Controlled expression of cancer-associated genes in the system offers a way to examine tumour formation over space and time.
  Nicolò Riggi
  Felipe de Sousa e Melo
  
  News & Views24 Apr 2024
- Ancient DNA traces family lines and political shifts in the Avar empire
  
  Genetic pedigrees spanning nine generations uncover the social organization of a nomadic empire that dominated much of central and eastern Europe from the sixth to the early ninth century.
  Lara M. Cassidy
  
  News & Views24 Apr 2024
- A chemical method for selective labelling of the key amino acid tryptophan
  
  Research Briefing24 Apr 2024
- Galaxy found napping in the primordial Universe
  Jacqueline Antwi-Danso
  
  News & Views24 Apr 2024
- Tumours form without genetic mutations
  Anne-Kathrin Classen
  
  News & Views24 Apr 2024
- Marsupial genomes reveal how a skin membrane for gliding evolved
  Darío G. Lupiáñez
  
  News & Views24 Apr 2024

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Latest Research articles

Structures of human γδ T cell receptor–CD3 complex

Weizhi Xin
Bangdong Huang
Qiang Zhou
Article24 Apr 2024
High-performance fibre battery with polymer gel electrolyte

A fibre lithium-ion battery that can potentially be woven into textiles shows enhanced battery performance and safety compared with liquid electrolytes.

Chenhao Lu
Haibo Jiang
Huisheng Peng
Article24 Apr 2024
Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

HRO761 is a potent, selective, allosteric WRN inhibitor that binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation.

Stephane Ferretti
Jacques Hamon
Marta Cortés-Cros
ArticleOpen Access24 Apr 2024
Antisense oligonucleotide therapeutic approach for Timothy syndrome

Antisense oligonucleotides effectively decrease the inclusion of exon 8A of CACNA1C in human cells both in vitro and in rodents transplanted with human brain organoids, and a single intrathecal administration rescued both calcium changes and in vivo dendrite morphology of patient neurons.

Xiaoyu Chen
Fikri Birey
Sergiu P. Pașca
ArticleOpen Access24 Apr 2024
Multi-project wafers for flexible thin-film electronics by independent foundries

The iconic 6502 microprocessor designed in two key thin-film transistor technologies by independent foundries is used to demonstrate and expand the multi-project wafer approach for flexible electronics.

Hikmet Çeliker
Wim Dehaene
Kris Myny
ArticleOpen Access24 Apr 2024

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Medical devices in China

Recent government policy changes have encouraged Chinese hospitals to look to suppliers based in China for their equipment and materials.

Spotlight 20 Mar 2024

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W2 Professorship with tenure track to W3 in Animal Husbandry (f/m/d)

The Faculty of Agricultural Sciences at the University of Göttingen invites applications for a temporary professorship with civil servant status (g...

Göttingen (Stadt), Niedersachsen (DE)

Georg-August-Universität Göttingen
W1 professorship for „Tissue Aspects of Immunity and Inflammation“

Kiel University (CAU) and the University of Lübeck (UzL) are striving to increase the proportion of qualified female scientists in research and tea...

Lübeck

University of Luebeck
W1 professorship for "Bioinformatics and artificial intelligence that preserve privacy"

Kiel University (CAU) and the University of Lübeck (UzL) are striving to increase the proportion of qualified female scientists in research and tea...

Kiel, Schleswig-Holstein (DE)

Universität Kiel - Medizinische Fakultät
W1 professorship for "Central Metabolic Inflammation“

Kiel University (CAU) and the University of Lübeck (UzL) are striving to increase the proportion of qualified female scientists in research and tea...

Lübeck

University of Luebeck
W1 professorship for "Congenital and adaptive lymphocyte regulation"

Kiel University (CAU) and the University of Lübeck (UzL) are striving to increase the proportion of qualified female scientists in research and tea...

Kiel, Schleswig-Holstein (DE)

Universität Kiel - Medizinische Fakultät

Do cutting-edge CAR-T-cell therapies cause cancer? What the data say

How reliable is this research? Tool flags papers discussed on PubPeer

First fetus-to-fetus transplant demonstrated in rats

Optical clocks at sea

Daily briefing: Gaze upon the most detailed Moon maps ever made

News & Comment

Why doing science is difficult in India today

Do cutting-edge CAR-T-cell therapies cause cancer? What the data say

First fetus-to-fetus transplant demonstrated in rats

What China’s mission to collect rocks from the far side could reveal about the Moon

Epic blazes threaten Arctic permafrost. Can fire-fighters save it?

Superconductivity hunt gets boost from China's $220 million physics 'playground'

How reliable is this research? Tool flags papers discussed on PubPeer

Latest Reviews & Analysis

Elephant-nose fish ‘see’ farther by electric sensing when in groups

Robust optical clocks promise stable timing in a portable package

Targeting RNA opens therapeutic avenues for Timothy syndrome

Bioengineered ‘mini-colons’ shed light on cancer progression

Ancient DNA traces family lines and political shifts in the Avar empire

A chemical method for selective labelling of the key amino acid tryptophan

Galaxy found napping in the primordial Universe

Tumours form without genetic mutations

Marsupial genomes reveal how a skin membrane for gliding evolved

Latest Research articles

Structures of human γδ T cell receptor–CD3 complex

High-performance fibre battery with polymer gel electrolyte

Discovery of WRN inhibitor HRO761 with synthetic lethality in MSI cancers

Antisense oligonucleotide therapeutic approach for Timothy syndrome

Multi-project wafers for flexible thin-film electronics by independent foundries

Collections

Medical devices in China

Trending - Altmetric

Science jobs

W2 Professorship with tenure track to W3 in Animal Husbandry (f/m/d)

W1 professorship for „Tissue Aspects of Immunity and Inflammation“

W1 professorship for "Bioinformatics and artificial intelligence that preserve privacy"

W1 professorship for "Central Metabolic Inflammation“

W1 professorship for "Congenital and adaptive lymphocyte regulation"

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Transient loss of Polycomb components induces an epigenetic cancer fate

Phylogenomics and the rise of the angiosperms

WHO redefines airborne transmission: what does that mean for future pandemics?

Bird flu virus has been spreading in US cows for months, RNA reveals

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