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The need for cell lines from diverse ethnic backgrounds for prostate cancer research

Nature Reviews Urology volume 16, pages 691–692 (2019)Cite this article

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Cell lines are valuable tools for developing treatments to minimize disparities in prostate cancer outcomes. Nevertheless, limitations in their application, primarily from the inadequate use of ethnically diverse cell lines, continue to hinder the advance of drug leads that would equally benefit men from both African and European ancestry.

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Fig. 1: The ethnic representation of panels of cancer cell lines according to tissue specificity on the ATCC website.

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Authors and Affiliations

  1. Department of Basic Medical Sciences, Faculty of Medical Sciences, University of the West Indies, Kingston, Jamaica

    Simone Badal & Henkel Valentine

  2. Blood Cell Development and Function Program, Cell Culture Facility, Fox Chase Cancer Center, Philadelphia, PA, USA

    Kerry S. Campbell

  3. Cancer Prevention and Control Program, Fox Chase Cancer Center, Philadelphia, PA, USA

    Camille Ragin

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  1. Simone Badal
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  2. Kerry S. Campbell
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  3. Henkel Valentine
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  4. Camille Ragin
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Correspondence to Simone Badal.

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Badal, S., Campbell, K.S., Valentine, H. et al. The need for cell lines from diverse ethnic backgrounds for prostate cancer research. Nat Rev Urol 16, 691–692 (2019). https://doi.org/10.1038/s41585-019-0234-y

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