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PROSTATE CANCER

PSMA PET–CT redefines nonmetastatic castration-resistant prostate cancer

New data show that prostate-specific membrane antigen (PSMA) PET–CT can reveal the anatomical location of prostate cancer recurrences in patients diagnosed with nonmetastatic castration-resistant disease according to conventional imaging. The findings necessitate a new evaluation of the role of PSMA PET–CT in this setting compared with standard-of-care imaging and treatment approaches.

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Fig. 1: PSMA PET–CT detection of prostate cancer metastases.

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Correspondence to Piet Ost.

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P.O. holds institutional research grants from Bayer, Ferring, Merck and Varian, has received consultancy fees from Bayer, Ferring and Janssen, and travel support from Ferring, with all funds going to his institution.

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Ost, P. PSMA PET–CT redefines nonmetastatic castration-resistant prostate cancer. Nat Rev Urol 17, 133–134 (2020). https://doi.org/10.1038/s41585-019-0268-1

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