Abstract
Calculating the rate of evolution in terms of nucleotide substitutions seems to give a value so high that many of the mutations involved must be neutral ones.
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References
Zuckerkandl, E., and Pauling, L., in Evolving Genes and Proteins (edit. by Bryson, V., and Vogel, H. J.), 97 (Academic Press, New York, 1965).
Buettner-Janusch, J., and Hill, R. L., in Evolving Genes and Proteins (edit. by Bryson, V., and Vogel, H. J.), 167 (Academic Press, New York, 1965).
Margoliash, E., and Smith, E. L., in Evolving Genes and Proteins (edit. by Bryson, V., and Vogel, H. J.), 221 (Academic Press, New York, 1965).
Kaplan, N. O., in Evolving Genes and Proteins (edit. by Bryson, V., and Vogel, H. J.), 243 (Academic Press, New York, 1965).
Sager, R., and Ryan, F. J., Cell Heredity (John Wiley and Sons, New York, 1961).
Sueoka, N., J. Mol. Biol., 3, 31 (1961).
Muller, H. J., Bull. Amer. Math. Soc., 64, 137 (1958).
Kimura, M., Genet. Res. (in the press).
Haldane, J. B. S., J. Genet., 55, 511 (1957).
Kimura, M., J. Genet., 57, 21 (1960).
Kimura, M., Ann. Math. Stat., 28, 882 (1957).
Mukai, T., Genetics, 50, 1 (1964).
Harris, H., Proc. Roy. Soc., B, 164, 298 (1966).
Hubby, J. L., and Lewontin, R. C., Genetics, 54, 577 (1966).
Lewontin, R. C., and Hubby, J. L., Genetics, 54, 595 (1966).
Narise, S., and Hubby, J. L., Biochim. Biophys. Acta, 122, 281 (1966).
Fincham, J. R. S., Genetic Complementation (Benjamin, New York, 1966).
Muller, H. J., in Heritage from Mendel (edit. by Brink. R. A.), 419 (University of Wisconsin Press, Madison, 1967).
Kimura, M., Genet. Res., 9, 23 (1967).
Report of the United Nations Scientific Committee on the Effects of Atomic Radiation (New York, 1958).
Kimura, M., and Crow, J. F., Genetics, 49, 725 (1964).
Watson, J. D., Molecular Biology of the Gene (Benjamin, New York, 1965).
Wright, S., Genetics, 16, 97 (1931).
Mayr, E., Animal Species and Evolution (Harvard University Press. Cambridge, 1965).
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KIMURA, M. Evolutionary Rate at the Molecular Level. Nature 217, 624–626 (1968). https://doi.org/10.1038/217624a0
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DOI: https://doi.org/10.1038/217624a0
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