Preclinical Reproducibility and Robustness

Preclinical Reproducibility and Robustness

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1-20 of 31 ARTICLES
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Featured Article
https://doi.org/10.12688/f1000research.11808.2
Research Article metrics
Revised
Proteolytic processing of the L-type Ca2+ channel alpha11.2 subunit in neurons
[version 2; peer review: 3 approved]
Olivia R. Buonarati, Peter B. Henderson, Geoffrey G. Murphy, Mary C. Horne, Johannes W. Hell
Peer Reviewers Annette C. Dolphin; Jörg Striessnig; Mark L. Dell’Acqua
  • Funders
  • American Heart Association
  • National Institutes of Health
LATEST VERSION PUBLISHED 17 Aug 2018
https://doi.org/10.12688/f1000research.27217.2
Opinion Article metrics
Revised
Cancer T-cell therapy: building the foundation for a cure
[version 2; peer review: 3 approved]
Alexander Kamb, William Y. Go
Peer Reviewers John R. James and Muna Fuyal; Barbra J. Sasu; C. Glenn Begley
  • Funder
  • A2 Biotherapeutics, Inc.
LATEST VERSION PUBLISHED 22 Dec 2020
https://doi.org/10.12688/f1000research.25573.2
Research Article metrics
Registered report
Revised
Stage 2 Registered Report: How subtle linguistic cues prevent unethical behaviors
[version 2; peer review: 2 approved]
Wen Guo, Huanxu Liu, Jingwen Yang, Yuqi Mo, Can Zhong, Yuki Yamada
Peer Reviewers Sergio Cervera-Torres; Michiko Asano
  • Funder
  • Japan Society for the Promotion of Science
LATEST VERSION PUBLISHED 16 Nov 2020
https://doi.org/10.12688/f1000research.24494.2
Research Article metrics
Revised
An inexpensive and easy-to-implement approach to a Quality Management System for an academic research lab
[version 2; peer review: 2 approved, 1 approved with reservations]
Michael Hewera, Ann-Christin Nickel, Nina Knipprath, Sajjad Muhammad, Xiaolong Fan, Hans-Jakob Steiger, Daniel Hänggi, Ulf Dietrich Kahlert
Peer Reviewers Jan Vollert; Judith J. de Haan and Frank Miedema; Clarissa Carneiro and Olavo B. Amaral
  • Funder
  • Bundesministerium für Bildung und Forschung
LATEST VERSION PUBLISHED 06 Aug 2020
https://doi.org/10.12688/f1000research.20183.4
Study Protocol metrics
Registered report
Revised
Stage 1 Registered Report: How subtle linguistic cues prevent unethical behaviors
[version 4; peer review: 2 approved]
Wen Guo, Huanxu Liu, Jingwen Yang, Yuqi Mo, Can Zhong, Yuki Yamada
Peer Reviewers Michiko Asano; Sergio Cervera-Torres
  • Funder
  • Japan Society for the Promotion of Science
LATEST VERSION PUBLISHED 12 Mar 2020
https://doi.org/10.12688/f1000research.15869.1
Study Protocol metrics
Identifying stroke therapeutics from preclinical models: A protocol for a novel application of network meta-analysis
[version 1; peer review: 2 approved]
Manoj M. Lalu, Dean A. Fergusson, Wei Cheng, Marc T. Avey, Dale Corbett, Dar Dowlatshahi, Malcolm R. Macleod, Emily S. Sena, David Moher, Risa Shorr, Sarah K. McCann, Laura J. Gray, Michael D. Hill, Annette O'Connor, Kristina Thayer, Fatima Haggar, Aditi Dobriyal, Hee Sahng Chung, Nicky J. Welton, Brian Hutton
Peer Reviewers Peter-Paul Zwetsloot; Hanna M. Vesterinen
  • Funders
  • University of Bristol
  • National Institute for Health Research
  • University Hospitals Bristol NHS Foundation Trust
  • Ottawa Hospital
  • University of Ottawa
  • Canadian Institutes of Health Research
PUBLISHED 03 Jan 2019
https://doi.org/10.12688/f1000research.14584.1
Research Article metrics PEER REVIEW DISCONTINUED
Reanalysis
Individual typological differences in a neurally distributed semantic processing system: Revisiting the Science article by Mitchell et al. on computational neurolinguistics
[version 1; peer review: 1 approved with reservations]
Hiroyuki Akama
Peer Reviewer Chiu-Hsieh Hsu
PUBLISHED 24 Apr 2018
https://doi.org/10.12688/f1000research.9611.3
Research Article metrics
Reanalysis
Revised
Revisiting inconsistency in large pharmacogenomic studies
[version 3; peer review: 2 approved, 1 approved with reservations]
Zhaleh Safikhani, Petr Smirnov, Mark Freeman, Nehme El-Hachem, Adrian She, Quevedo Rene, Anna Goldenberg, Nicolai J. Birkbak, Christos Hatzis, Leming Shi, Andrew H. Beck, Hugo J.W.L. Aerts, John Quackenbush, Benjamin Haibe-Kains
Peer Reviewers Michael T. Hallett; Paul T. Spellman; David G. Covell
  • Funders
  • Terry Fox Research Institute
  • The Villum Kann Rasmussen Foundation
  • Princess Margaret Cancer Centre
  • National Heart, Lung, and Blood Institute
  • National Natural Science Foundation of China
  • Canadian Institutes of Health Research
  • Ontario Institute for Cancer Research
  • Cancer Research Society
  • National High Technology Research and Development Program of China
  • Yale University
  • NCI GAME-ON Cancer Post-GWAS
  • Canadian Cancer Society Research Institute
LATEST VERSION PUBLISHED 11 Aug 2017
https://doi.org/10.12688/f1000research.11438.2
Research Article metrics
Revised
The dynamic upper limit of human lifespan
[version 2; peer review: 1 approved, 2 approved with reservations]
Saul Newman, Simon Easteal
Peer Reviewers Jean-Michel Gaillard; Michael R. Rose and Laurence D Mueller; James Vaupel and José Manuel Aburto
LATEST VERSION PUBLISHED 09 Jun 2017
https://doi.org/10.12688/f1000research.11334.1
Review metrics
Reproducibility2020: Progress and priorities
[version 1; peer review: 2 approved]
Leonard P. Freedman, Gautham Venugopalan, Rosann Wisman
Peer Reviewers Michael S. Lauer; Lenny Teytelman
PUBLISHED 02 May 2017
https://doi.org/10.12688/f1000research.11055.1
Research Article metrics
Replication of the principal component analyses of the human genome diversity panel
[version 1; peer review: 1 approved, 1 approved with reservations]
Thomas Charlon, Alessandro Di Cara, Sviatoslav Voloshynovskiy, Jérôme Wojcik
Peer Reviewers Zoltán Kutalik; Michael G. B. Blum
  • Funder
  • European Federation of Pharmaceutical Industries and Associations
PUBLISHED 15 Mar 2017
https://doi.org/10.12688/f1000research.9918.1
Antibody Validation Article metrics
Evaluation of recombinant monoclonal antibody SVmab1 binding to NaV1.7 target sequences and block of human NaV1.7 currents
[version 1; peer review: 3 approved]
Dong Liu, Mandy Tseng, Linda F. Epstein, Lydia Green, Brian Chan, Brian Soriano, Desiree Lim, Oscar Pan, Christopher M. Murawsky, Chadwick T. King, Bryan D. Moyer
Peer Reviewers David Hackos; Alan D. Wickenden and Wilson Edwards; Theodore Cummins
PUBLISHED 25 Nov 2016
https://doi.org/10.12688/f1000research.9448.2
Research Note metrics
Revised
A research note regarding "Variation in cancer risk among tissues can be explained by the number of stem cell divisions"
[version 2; peer review: 2 approved]
Maxime Tarabichi, Vincent Detours
Peer Reviewers Benjamin Roche and Cindy Gidoin; Maddalena Fratelli and Marco Bolis
LATEST VERSION PUBLISHED 10 Nov 2016
https://doi.org/10.12688/f1000research.8731.2
Research Article metrics
Revised
Results of an attempt to reproduce the STAP phenomenon
[version 2; peer review: 2 approved]
Shinichi Aizawa
Peer Reviewers Austin Smith; Irene de Lazaro
LATEST VERSION PUBLISHED 17 Oct 2016
https://doi.org/10.12688/f1000research.9471.2
Research Article metrics
Revised
Whose sample is it anyway? Widespread misannotation of samples in transcriptomics studies
[version 2; peer review: 2 approved, 1 approved with reservations]
Lilah Toker, Min Feng, Paul Pavlidis
Peer Reviewers Leonard P. Freedman; Hans van Bokhoven; Levi Waldron
LATEST VERSION PUBLISHED 30 Sep 2016
https://doi.org/10.12688/f1000research.9144.1
Research Note metrics
A reanalysis of “Two types of asynchronous activity in networks of excitatory and inhibitory spiking neurons”
[version 1; peer review: 2 approved]
Rainer Engelken, Farzad Farkhooi, David Hansel, Carl van Vreeswijk, Fred Wolf
Peer Reviewers Jonathan Touboul; Maoz Shamir
PUBLISHED 22 Aug 2016
https://doi.org/10.12688/f1000research.9202.1
Research Article metrics
Does sadness impair color perception? Flawed evidence and faulty methods
[version 1; peer review: 2 approved]
Alex O. Holcombe, Nicholas J. L. Brown, Patrick T. Goodbourn, Alexander Etz, Sebastian Geukes
Peer Reviewers Sophie von Stumm; Michael A Crognale
PUBLISHED 21 Jul 2016
https://doi.org/10.12688/f1000research.7822.2
Research Note metrics
Revised
GPR21 KO mice demonstrate no resistance to high fat diet induced obesity or improved glucose tolerance
[version 2; peer review: 1 approved, 2 approved with reservations]
Jinghong Wang, Zheng Pan, Helene Baribault, Danny Chui, Caroline Gundel, Murielle Véniant
Peer Reviewers Mary Pelleymounter; Richard Neubig; Michelle Kimple
LATEST VERSION PUBLISHED 17 Jun 2016
https://doi.org/10.12688/f1000research.8753.1
Research Article metrics
Early-childhood housing mobility and subsequent PTSD in adolescence: a Moving to Opportunity reanalysis
[version 1; peer review: 2 approved]
David C. Norris, Andrew Wilson
Peer Reviewers Ewout W. Steyerberg; Fred Hasselman
PUBLISHED 27 May 2016
https://doi.org/10.12688/f1000research.8705.1
Research Note metrics
Assessment of pharmacogenomic agreement
[version 1; peer review: 3 approved]
Zhaleh Safikhani, Nehme El-Hachem, Rene Quevedo, Petr Smirnov, Anna Goldenberg, Nicolai Juul Birkbak, Christopher Mason, Christos Hatzis, Leming Shi, Hugo JWL Aerts, John Quackenbush, Benjamin Haibe-Kains
Peer Reviewers Weida Tong; Terence Speed; Yudi Pawitan
PUBLISHED 09 May 2016
1-20 of 31 ARTICLES
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