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DRUG DEVELOPMENT

A new approach for inflammatory bowel disease therapy

A new drug restores a compromised intestinal barrier and ameliorates colitis in mice by modulating paracellular permeability through a newly discovered mechanism.

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Fig. 1: Divertin can restore tight junction function in models of IBD.

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Correspondence to J. Magarian Blander.

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Blander, J.M. A new approach for inflammatory bowel disease therapy. Nat Med 25, 545–546 (2019). https://doi.org/10.1038/s41591-019-0416-4

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