The protein tau forms abnormal filamentous aggregates called tangles in the brains of people with neurodegeneration. Structures of two such filaments offer pathways to a deeper understanding of Alzheimer's disease. See Article p.185
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Eisenberg, D., Sawaya, M. Taming tangled tau. Nature 547, 170–171 (2017). https://doi.org/10.1038/nature23094
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DOI: https://doi.org/10.1038/nature23094
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